“Doctor, it has to be frozen shoulder! How can you not see it?!”
After years in clinics, I’ve occasionally encountered impatient family members—frustrated by a loved one’s pain who don’t want more tests and just want fast answers, hoping to jump straight to treatment so the patient feels better.

Having treated many stubborn frozen shoulder cases, I fully understand why they’re anxious—the sore arm, the nights woken up by pain. Many travel far after Googling symptoms and thinking “specialized doctors” can diagnose frozen shoulder in a glance—only to face a full evaluation, palpation, imaging, and more.

I greet this with a gentle smile and appreciate their trust in my expertise. Yes, frozen shoulder is usually easy to diagnose—and many patients can self‑assess with online quizzes—but for physicians, it’s even more critical to rule out what isn’t frozen shoulder. Many conditions present with similar symptoms or neck‑shoulder stiffness.

Moreover, if the frozen shoulder is triggered by another systemic condition, treatment and rehabilitation become very different—requiring personalized exercise and nutritional guidance. That’s why a precise distinction is essential!


13 Conditions That Mimic or Commonly Accompany Frozen Shoulder

Last time I shared nine shoulder pain diagnoses other than frozen shoulder. Now, here are conditions that can cause joint pain, sleep disturbance, or often co-occur with shoulder and neck tension. Adapted from Dr. Xu Hong‑zhi’s Pain Cured: Understand, Relieve, and Prevent Pain—a fantastic resource.

1. Myofascial (Muscle‑Fascia) Pain Syndrome
Often mistaken for frozen shoulder. Common in sedentary office workers, smartphone users, or tablet users. Patients seek strong massage or salty food, prefer deep pressure massage, and often experience headaches, nausea, or chest tightness—sometimes mistaken for cardiac pain.

2. Rheumatoid Arthritis
An autoimmune disease causing joint pain and inflammation, with tenderness on pressure. Usually affects wrists, hands, knees, and ankles more than shoulders, though shoulder involvement can occur.

3. Systemic Lupus Erythematosus
Another autoimmune disease—unlike RA, it often affects larger joints (hips, knees, shoulders). Symptoms include bone and joint pain and limited motion.

4. Polymyalgia Rheumatica
Causes proximal shoulder and hip pain, especially in older adults. Diagnosed partly by elevated erythrocyte sedimentation rate via blood tests.

5. Multi‑Joint Osteoarthritis
Like frozen shoulder, it affects joints—but osteoarthritis is cartilage wear and bone friction. X‑rays show joint degeneration. Shoulder osteoarthritis often occurs in younger laborers who lift heavy loads routinely.

6. Polymyositis
Presents as symmetric proximal upper/lower limb muscle weakness (upper arms and thighs). While frozen shoulder patients may feel unilateral arm weakness, polymyositis involves both sides.

7. Hypothyroidism
Frozen shoulder sufferers often have night pain, fatigue, sleep disturbance, and reduced activity accompanied by weight gain. Hypothyroid patients often feel lethargic and gain weight similarly—and thyroid dysfunction is linked to frozen shoulder incidence.

8. Hyperparathyroidism
Causes neck‑shoulder muscle tension, nausea, poor sleep, fatigue, and hypertension. Symptoms may overlap with hyperparathyroidism, including mood issues, bone pain, and high calcium levels.

9. Sleep Apnea
Night awakenings in frozen shoulder patients aren’t always pain—they might feel an urge to move. Sleep apnea interrupts sleep quality and can cause frequent arousals.

10. Cushing’s Syndrome
Symptoms include muscle weakness worsened by inactivity and low potassium, atrophy of type II muscle fibers—leading to reduced limb activity. Classic signs: “buffalo shoulder,” central obesity with thin limbs, osteoporosis-induced back pain or rib/spine fractures.

11. Addison’s Disease
The opposite of Cushing’s—insufficient adrenal cortex hormones. Both conditions feature osteoporosis and muscle weakness affecting musculoskeletal health. Addison’s presents as slowly progressive fatigue, muscle weakness, appetite loss and weight decrease, and sudden bone pain or fractures.

12. Multiple Sclerosis
A central nervous system autoimmune disease causing demyelination. Symptoms include sudden numbness, weakness, ataxia, progressing ultimately to chronic stiffness, cramps, and limb spasticity.

13. Nerve Root Compression (Neuropathy)
Causes neck‑shoulder tightness—but unlike frozen shoulder, there typically is no true motion limit. The shoulder can still be raised, but tingling, numbness, or radiating pain differ from capsular restriction.


When patients say “my shoulder hurts,” doctors mentally review a textbook of possibilities. If your physician recommends more tests rather than jumping to the frozen‑shoulder label, please understand—they may be clarifying the core issue so treatment isn’t misplaced.


References

  • Shibli‑Rahhal A., Van Beek M., Schlechte J. A. (2006). Cushing’s syndrome. Clinics in Dermatology, 24(4), 260–265.
  • Aloia J. F., Roginsky M., Ellis K., Shukla K., Cohn S. (1974). Skeletal metabolism and body composition in Cushing’s syndrome. Journal of Clinical Endocrinology & Metabolism, 39(6), 981–985.